DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...
Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic ...
S. aureus has been identified as a common secondary bacterial coinfection agent for different respiratory viruses. Several investigations have revealed that coinfection with the influenza A virus (IAV ...
Among model organisms, bacteria hold a unique place, as both models of infection and pathogenesis, and as research tools. More to the point, molecular biology was built upon the cell walls of lowly ...
BioRxiv (2023) PubMed PMID: 37546940; PubMed Central PMCID: PMC10402079. The mammalian innate immune system uses cyclic GMP–AMP synthase (cGAS) to synthesize the cyclic dinucleotide 2′,3′-cGAMP during ...
Bacteriophages, or phages for short, are viruses that infect bacteria. Using phages therapeutically could be very useful in fighting antibiotic-resistant pathogens, but the molecular interactions ...
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