Imagine you work for a hypothetical gene synthesis company, one of dozens around the world that manufacture tiny strands of custom nucleic acids like DNA for customers in academia and industry. DNA ...

DNA contains foundational information needed to sustain life. Understanding how this information is stored and organized has been one of the greatest scientific challenges of the last century. With ...

Decades of research has viewed DNA as a sequence-based instruction manual; yet every cell in the body shares the same genes – so where is the language that writes the memory of cell identities?

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in ...

DNA sequencing is one of today's most critical scientific fields, powering leaps in humanity's understanding of genetic causes of cancer, neurodegenerative diseases, and diabetes. One issue facing the ...

Breakthroughs, discoveries, and DIY tips sent every weekday. Terms of Service and Privacy Policy. In 1976, workers excavating a tunnel for the Toronto subway system ...

Caption main figure: The rigid base-pair model is forced, using 28 constraints (indicated by red spheres), into a lefthanded superhelical path that mimics the DNA conformation in the nucleosome.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...