Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young ...

A research team at the Medical University of Vienna has discovered a new approach to treating a particularly frequent and ...

After decades of fixating on mutations in nuclear DNA as the prime suspects in cancer development, researchers are increasingly peering into the cell’s powerhouse for clues. Mutations in mitochondrial ...

Zoldonrasib targets KRAS G12D-mutated non-small cell lung cancer, receiving FDA breakthrough therapy designation for its ...

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, ...

ETX-19477 is a potent, selective inhibitor of poly (ADP-ribose) glycohydrolase (PARG), an enzyme that plays a role in the DNA ...

The study, published in British scientific journal Nature, suggests that the disease may begin in basal stem cells — ...

Tanning beds promise a quick glow, but a new study says the real cost is written deep into your skin. Researchers have found ...

Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wrapping and unwrapping DNA, and even minor missteps can lead to ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...