Research on gastrointestinal diseases, especially cancer, has mainly focused on epithelial cells, which line the surfaces of organs, are important for various functions, and are believed to be the ...

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited ...

A new method vastly improves on the existing approach for single-cell genetic sequencing, enabling scientists to read the genomes of individual cells and viral particles in the environment more ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research ...

A micrograph shows several individual microcapsules including one, brightly lit one in the lower right corner, that contains amplified DNA from a single particle. A new method vastly improves on the ...