From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...

Somatic testing analyzes genetic material in specific cells or tissues to identify acquired mutations, revolutionizing oncology by enhancing diagnosis, prognosis, and treatment strategies. This ...

Faculty in the Statistics in Genomics and Genetics Hub develop statistical and computational methods for analyzing high-throughput genomic and epigenomic data to advance biological discovery in cancer ...

Scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints of a potential new ...

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...

Two months later, Gould began to experience a strange cascade of symptoms. His ankles swelled to the width of his calves. The right side of his face became so bloated that he could not open his eye.

Proteogenomics explores how genetic information translates into protein expression and function, and the role of changes across DNA, RNA, and proteins in influencing disease development and ...